Genetic Engineering and Diseases - Gene Drive & Malaria

  • Published: 21 September 2016
  • We have the choice to attack one of our oldest enemies with genetic engineering. But should we do it?
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    Big thanks to James Gurney and Roya Haghighat-Khah for their help and advice with this video!
    Lucien Delbert, Mike C, Ricardo Chavarria, Juha Wellman, Zachary Jordan, Patrick Chang, Adrian Mihali, Nicodemos Nicodemou, Lacey Larson, Austin Earnest, Andre Wee, Koroslak, Alex Brady, Roberto Cano, Andreas Stokholm, Plamen Ivanov, E Smith, Kieran Hunter-East, Christopher Trinh, Tony Kwok, Adam Rabenstein, Andrew Whitehurst, Alena Vlachova, Mackenzie Broadbent, Andreas Hertle, Martin Petersen, Kasturi Raghavan, Gregory Griffin, KiaTheDead, Aaron Stevens, Jimmy C, Benedikt Jaletzke, Jonathan Bowler, Zdravko Šašek, Wouter Stokhof, Zealotus, Long Vu, Fatman13, Jeremy Dumet, Miles Spoor, Mirton I, Al Fl, Jonathan Carter, Stanislaw Wasowicz, Marek Turcani, Francisco Santos, Justin Choi, Dagoberto Chapa, Chip Salzenberg, TinFung, Bob Bergeron, Peer, Justin Elstrott, Rachid Malik, Octavio Astillo, Romain Isnel, Rich Sekmistrz, Kuosora, Mozart Petter, Justin Jeffries, Nicola Licheri, Bahram Malaekeh, Florent Petterschmitt, David Mark, Gaby Germanos, Shweta Bharadwai, Lux Stamm, Marc Johann, Joe, Nefaur Khandker, Anders Madsen, Sarah Yoshi, monoxide, Brandon Meador, Dovydas Bartkevicius, Tyler Vigen, Michael Niella, Gordon Timilty, Slava Dzyba, Bagel Krippen Chandra, KodinCage, Miikka Harjuntausta, Magid Elgady, Vince Houmes, Irae Carvalho, Josh Talbot, Mr.Z, Pawel Urbanek, Russ Clarke, Lucas Tostes, Oscar Chamaria, Zachary Langdon, Steve Bollenbaugh, Xiaogiang Zheng, Peter LoPinto, Jenny Nordenborg, Evan Faas, Greg Fowler, Cicmil Mladen, Canut Durgun, Malovich, Cedric, Dave Anderson, Jones, Elliot, Denis Dube, David Allen, Dawson Reid, Jake Zwirdowski, Denis Leu

    Harvard FAQs on gene drive:
    Research paper on using CRISPR for malaria gene drive:
    Nature article on engineered mosquitos:
    STAT new article on using gene drive against Zika:
    Tech review article on using gene drive against malaria:
    Smithsonian on deadliness of mosquitos:
    Science article about the risks of the technology:
    New Yorker on Pros and Cons:
    Gates note on death rate through mosquitos:
    Status quo on field trial in the U.S.:
    Evolution working against gene drive technology:
    Research paper on evolution of resistance against gene drive:
    Science news on possible safety feature for gene drive:
    Help us caption & translate this video!

Comments • 18 546

  • Kurzgesagt – In a Nutshell
    Kurzgesagt – In a Nutshell   Před 6 měsíci

    There's brand new stuff in the Kurzgesagt Merch Shop. Check it out here:

    • Mohit Saxena
      Mohit Saxena  Před 2 dny

      How is a simple pigeon going to stop a moster

      • :Amadeus :Țurcanu-Moisl.

        [ if all the carnivores would be put on a mosquito-diet, we could erradicate world hunger. Bonus: they would save the vegans from malaria, which could be the final- cause for the world-peace to break out. Or so... ]

        • Qw Qwel
          Qw Qwel  Před 9 dny

          actually it happened 3 years ago

          • Qw Qwel
            Qw Qwel  Před 9 dny

            Kurzgesagt I was bitten by mosquitoes, purple mosquitoes, it's weird because there are no purple mosquitoes, and I immediately searched on google but there were no results, are there purple mosquitoes?

            • B0RED EDGE
              B0RED EDGE  Před 52 minutami


              • TCS15
                TCS15  Před hodinou

                Mosquito Kingdom, the home of Malario.

                • Yasmine Hussien
                  Yasmine Hussien  Před 3 hodinami

                  I get bitten by billions of these where is the malaria?

                  • FritzPlay !
                    FritzPlay !  Před 5 hodinami

                    We need malaria because then we might suffer overpopulation because world is allredy stressing its self with food prodoction Sorry for my bad spelling😂

                    • E Dab
                      E Dab  Před 9 hodinami

                      REVOLT!!!!!!!!!!!1!111! WE WANT A RABIES VIDEO

                      • E Dab
                        E Dab  Před 9 hodinami

                        You mean HIV is the deadliest for now.

                        • CREEPER AW MAN
                          CREEPER AW MAN  Před 10 hodinami

                          Malària its human invent

                          • MyNameIs IDK
                            MyNameIs IDK  Před 11 hodinami

                            Wow imagine this all like anime CELLS AT WORK

                            • Maks Dec
                              Maks Dec  Před 11 hodinami

                              Shields up, weapons on-line!

                              • Crusty Crab
                                Crusty Crab  Před 18 hodinami

                                We should genetically alter people so they don’t get the virus along with the mosquitos being genetically altered 🧐

                                • Destiny Ninja123
                                  Destiny Ninja123  Před 19 hodinami

                                  Malaria should be classified as an SCP.

                                  • Video Boy Gamer
                                    Video Boy Gamer  Před dnem

                                    I think we should use the technology.

                                    • Neroshi Interactive
                                      Neroshi Interactive  Před dnem

                                      So we must decide to use percentage of god power to save lives. Sound good then you think they be idiot start wars over it

                                      • The bear Potato
                                        The bear Potato  Před dnem

                                        In my humble opinion this needs more research before we should use it just to make sure it’s safe

                                        • Jeff Trahan
                                          Jeff Trahan  Před dnem

                                          Saying how hard it is to eliminate mosquitoes when we almost did it with dtd people just used it really fucking dumb

                                          • JustSnake X
                                            JustSnake X  Před dnem

                                            I know I didn’t just hear dick cells

                                            • Nevlin Thirta
                                              Nevlin Thirta  Před dnem

                                              Ppl that dislike this vid is big gay

                                              • camper tv
                                                camper tv  Před dnem

                                                I HATE YOU MALARIA

                                                • Stringed Monster
                                                  Stringed Monster  Před dnem

                                                  I've Been bited by 56 Mosquito and It's been a year when i got bited by 56 mosquitos And still nothing happens.. (I think it's because i have a vaccine in malaria..)

                                                  • Manchester
                                                    Manchester  Před dnem

                                                    I'm so scared right now

                                                    • LCFNTF
                                                      LCFNTF  Před dnem

                                                      Has anybody seen where some won said"oh god,a muto"

                                                      • Adek
                                                        Adek  Před dnem

                                                        fuck malaria and those little fuckers. Free the modified mosquitos!

                                                        • Pedro Mota
                                                          Pedro Mota  Před dnem

                                                          YES WE SHOULD attack malaria

                                                          • Darkest GamersTV
                                                            Darkest GamersTV  Před 2 dny

                                                            The technology is 7 years old now and I think we should get going by now.

                                                            • Nate Es
                                                              Nate Es  Před 2 dny

                                                              Let the children die. Perioooodddddt.

                                                              • ty becks
                                                                ty becks  Před 2 dny

                                                                Could crispr get into us through the mosquitoes

                                                                • Tobias Licht
                                                                  Tobias Licht  Před 2 dny

                                                                  Bitte Zombie-Virus!!!

                                                                  • saputra samsung
                                                                    saputra samsung  Před 2 dny

                                                                    Use it

                                                                    • Punpun Mart
                                                                      Punpun Mart  Před 2 dny

                                                                      i have malaria and the common cold at the same time and survived bro

                                                                      • Calamity
                                                                        Calamity  Před 2 dny

                                                                        The public is an ass. Ignorant people's opinion shouldn't matter in scientific debates.

                                                                        • love heart
                                                                          love heart  Před 2 dny

                                                                          Use it

                                                                          • R. Hasan
                                                                            R. Hasan  Před 2 dny

                                                                            100-200years ago people died very easily ....population was .controlled by the nature...but now with all these new techs people live longer and thus now we have 7 bilion of us....soon enough we would destroy this world

                                                                            • TEMPEST :-[
                                                                              TEMPEST :-[  Před 2 dny

                                                                              But malaria is also helping to control the human population.

                                                                              • TEMPEST :-[
                                                                                TEMPEST :-[  Před 2 dny

                                                                                Talk about microscopic Wolves in sheep skin.

                                                                                • Zhalfa Aulia
                                                                                  Zhalfa Aulia  Před 2 dny

                                                                                  hey why don't we injections imune cell to mosquitoes so a mosquito repellent instead of giving a disease but will provide curing

                                                                                  • ChewsWisely AMVs & Nightcore

                                                                                    sounds like leatherface

                                                                                    • mark 123
                                                                                      mark 123  Před 2 dny

                                                                                      do a video about the biggest fever of Philippines Dengue

                                                                                      • VPLS
                                                                                        VPLS  Před 2 dny

                                                                                        *EXECUTE ORDER 66*

                                                                                        • Antonym of Bright
                                                                                          Antonym of Bright  Před 2 dny

                                                                                          These are the ideas in life that are GOOD. We need to stop focusing on tiny, little minuscule topics and worry about *MOSSQEETOES.*

                                                                                          • BigBuster Bartholowmew
                                                                                            BigBuster Bartholowmew  Před 2 dny

                                                                                            cool story bro but how did all this fit in the monster's eye

                                                                                            • Mohit Saxena
                                                                                              Mohit Saxena  Před 2 dny

                                                                                              How is a simple pigeon going to stop a moster

                                                                                              • Khyrid
                                                                                                Khyrid  Před 2 dny

                                                                                                If there is one thing humans are good at, its driving species extinct by destroying their environment. Time to use it for a good reason.

                                                                                                • Hax Jason
                                                                                                  Hax Jason  Před 3 dny

                                                                                                  but mosquitos really don’t do anything to make the world a better place. it doesn’t even sustain balance in the food chain.

                                                                                                  • HelloThere131313
                                                                                                    HelloThere131313  Před 3 dny

                                                                                                    In Spanish, the suffix -ito means small, so a genetically modified mosquito that grew to a gigantic size would be called... EL MOSCO

                                                                                                    • Arcangelon Magus
                                                                                                      Arcangelon Magus  Před 16 hodinami

                                                                                                      "ito" "o" "ote"

                                                                                                      • Arcangelon Magus
                                                                                                        Arcangelon Magus  Před 16 hodinami

                                                                                                        Emmm. Noup. Mexican here. El mosco exist. Is a regular fly. You mean "El Moscote"

                                                                                                        • SecondPlayer 2P
                                                                                                          SecondPlayer 2P  Před 3 dny

                                                                                                          5:52 godzilla 2014 reference

                                                                                                          • FOOD
                                                                                                            FOOD  Před 3 dny

                                                                                                            Nah its fine not to use it. Theres too many humans in this world

                                                                                                            • Th&D4rkG3NEr^L
                                                                                                              Th&D4rkG3NEr^L  Před 3 dny

                                                                                                              I think the life have no price,and when are so many lifes in game ist a good idea to try

                                                                                                              • Mr. Meowser Monkey
                                                                                                                Mr. Meowser Monkey  Před 4 dny

                                                                                                                USE IT

                                                                                                                • Corsola Is The Best
                                                                                                                  Corsola Is The Best  Před 4 dny

                                                                                                                  ay ay ay Mosquito with malaria it's gay

                                                                                                                  • : Akame
                                                                                                                    : Akame  Před 4 dny

                                                                                                                    Why haven't we whipped them off the face of the earth?

                                                                                                                    • king b 47
                                                                                                                      king b 47  Před 4 dny

                                                                                                                      So basically in a few years when we have done all the testing we can get rid of malaria for good wow and I'll actually be here when it happens

                                                                                                                      • Backdad Schuh
                                                                                                                        Backdad Schuh  Před 4 dny

                                                                                                                        03:09 Humans shouldn' t play gods...

                                                                                                                        • 777 GAMER
                                                                                                                          777 GAMER  Před 4 dny

                                                                                                                          Everyday 1000 children will not die if there are no 1000 children Simple Just frickin control the population

                                                                                                                          • epic from epic games
                                                                                                                            epic from epic games  Před 4 dny

                                                                                                                            5:24 kurzgeagt: So, why haven't we done this? Me: Beacuse humans are so dumb that they're literally killing themselves and can't bother to save millions of lives beacuse they have other things to do

                                                                                                                            • Ameen Shindoli
                                                                                                                              Ameen Shindoli  Před 2 dny

                                                                                                                              Me: Because our politicians are too dumb and corrupted And soon those one eyed people are going to come here 😂

                                                                                                                              • Sho
                                                                                                                                Sho  Před 2 dny

                                                                                                                                there is a very valid reason to not try this just yet. What if it somehow goes horribly wrong? The technology is new and such a large scale project is dangerous. Worst case scenario the mosquitoes die, thereby affecting the whole food chain, which might even kill us.

                                                                                                                                • Dylan Sizemore
                                                                                                                                  Dylan Sizemore  Před 4 dny

                                                                                                                                  I say do it

                                                                                                                                  • Ricky Spanish
                                                                                                                                    Ricky Spanish  Před 4 dny

                                                                                                                                    I would smoke crack once before I die

                                                                                                                                    • BetaFrame098
                                                                                                                                      BetaFrame098  Před 4 dny

                                                                                                                                      I say develop a backup plan to eliminate the change in the event that the whole mission backfires before we release the mosquitos

                                                                                                                                      • Kai Swift
                                                                                                                                        Kai Swift  Před 4 dny

                                                                                                                                        Note to self, insta kill insects or avoid them at all costs.

                                                                                                                                        • Comic Sans
                                                                                                                                          Comic Sans  Před 4 dny

                                                                                                                                          They are kinda important to the ecosystem

                                                                                                                                          • vinuzo
                                                                                                                                            vinuzo  Před 5 dny

                                                                                                                                            The only reason we haven't done it yet is because the children dying are AFRICAN. Not white. I've always wondered how much differently America would react to malaria if someone smuggled 1 million African mosquitoes in a tank and let them all loose.

                                                                                                                                            • Mois Vater
                                                                                                                                              Mois Vater  Před 5 dny

                                                                                                                                              Kurzgesagt Is German and means short-term

                                                                                                                                              • Jäger The Fäger
                                                                                                                                                Jäger The Fäger  Před 5 dny

                                                                                                                                                This video gave me anxiety because i live in an area full of these shitheads

                                                                                                                                                • Judge Tater
                                                                                                                                                  Judge Tater  Před 5 dny

                                                                                                                                                  I say kill all mosquitoes. Fuck, kill the polar bears while we are at it lol. You know polar bears hunt humans!? "Aww noooo. I don't want my kids growing up in a world without polar bears!" Fuckin... why not!? You know if your kid met a polar bear, you probably are talking about your kid in past tense right!? Fuck em. Lol

                                                                                                                                                  • Aritra Bacchar2019
                                                                                                                                                    Aritra Bacchar2019  Před 5 dny

                                                                                                                                                    Saitama: oMg wHaT?

                                                                                                                                                    • Wolf Voigt
                                                                                                                                                      Wolf Voigt  Před 5 dny

                                                                                                                                                      Kill it with fire!!!

                                                                                                                                                      • Aqeel Sultan
                                                                                                                                                        Aqeel Sultan  Před 5 dny

                                                                                                                                                        population is explosion so malaria and others viruses try to make balance i prfer to die because malaria then by crowded

                                                                                                                                                        • two piece
                                                                                                                                                          two piece  Před 5 dny

                                                                                                                                                          This will 100% cause over population which has a higher negative effect than mosquitoes. I'de explian in further detail but it would take to much time.

                                                                                                                                                          • Catdev
                                                                                                                                                            Catdev  Před 5 dny

                                                                                                                                                            I agree with this. I think we should release these mosquitoes, but first test modified and non-modified to check if it works first.

                                                                                                                                                            • ghoul man oplo jj roblox

                                                                                                                                                              Is dingge

                                                                                                                                                              • Hunter
                                                                                                                                                                Hunter  Před 6 dny

                                                                                                                                                                if it was on my choose i would EDIT EVERYTHING! including gekos with wings. horses with horns y wings. Biggger much BIGGERs BETA FISHS and jumping spiders from the size of a tarantula. I also would would change ALL THE SPIDERS VENOM, REDUCING ITS EFFECT TO JUST A TEMPORARY PARALIZY. so no one would die anymore due snike bites and these animals would still use the venom to hunt. oh...and for last but not for least...I also would make fused animals and plants, creating a brand new fauna and flora. greetings from Brazil

                                                                                                                                                                • HerbertElayda
                                                                                                                                                                  HerbertElayda  Před 6 dny

                                                                                                                                                                  1. Eradicates Malaria 2. Human population spikes 3. Resources depletes more quickly 4. Game Over

                                                                                                                                                                  • TuffleGirl UwU
                                                                                                                                                                    TuffleGirl UwU  Před 6 dny

                                                                                                                                                                    Tho grim in my point of view its better to leave it alone or create better medcine the more we play god the more it drives things off to a worse future. Sure at first it may be nice to do this but what will happen to these children who are no longer dying as the world population grows even with their deaths. Humanity has already taken too much from nature that.. Continuing theses types of efforts would just cuase more problems.

                                                                                                                                                                    • lickplay Play
                                                                                                                                                                      lickplay Play  Před 6 dny

                                                                                                                                                                      NO USE

                                                                                                                                                                      • Halv Gud
                                                                                                                                                                        Halv Gud  Před 6 dny

                                                                                                                                                                        I think we should modify mosquitos to become extinct. This insect has no benefits for us humans nor is affecting the food chain too much. Also exterminating wasps would not be a bad idea. I hate wasps.

                                                                                                                                                                        • Blue Banana
                                                                                                                                                                          Blue Banana  Před 6 dny

                                                                                                                                                                          NO. Translating video titles and descriptions is NOT cool.